"Who is Cherry Buscemi?" Toby asked. "Is she Steve’s long-lost sister? A burlesque performer from the uncanny valley?"
It pairs unrelated concepts (like a celebrity surname and a physical act) to create a sense of confusion or humor.
: This part of the phrase seems to refer to a person or possibly a character from a movie, TV show, or another form of media. Without specific context, it's challenging to determine the exact reference, but it could be related to a public figure, an actor, or a character known for a particular trait or incident.