Advanced Organic Chemistry Practice Problems 2021 【100% Deluxe】

Predict the product of 4-chloropyridine with sodium methoxide in DMSO at 80°C.

Pd(OAc)₂ (5 mol%), NFSI (N-fluorobenzenesulfonimide, 1.2 equiv), ligand L1 (a bulky pyridine-oxazoline), DCE, 80 °C, 24 h. advanced organic chemistry practice problems 2021

: Some "advanced" sets still lean on 1980s chemistry. Useful reviews point out if the book includes modern catalysts (like Grubbs' catalysts for metathesis or Buchwald-Hartwig aminations ). ligand L1 (a bulky pyridine-oxazoline)