During the golden age of Warcraft III: The Frozen Throne (the engine that ran the original DotA), most players used default hotkeys. But professional cybercafés in the Philippines—Mineski’s home ground—had a unique problem. Many players grew up on LAN games like Counter-Strike and Warcraft III melee, using for camera control instead of the modern "edge-pan" or "grip drag."
The Mineski hotkey is a case study in "if it works, it works" — but is not recommended for new players due to ergonomic inefficiency.